2,5-DIOXO-4-IMIDAZOLIDINEACETIC ACID
2,5-dioxo-1,3-diazolidin-4-ylacetic acid
CAS: 5427-26-9
Molecular Formula: C5H6N2O4
2,5-DIOXO-4-IMIDAZOLIDINEACETIC ACID - Names and Identifiers
| Name | 2,5-dioxo-1,3-diazolidin-4-ylacetic acid |
| Synonyms | AKOS BBS-00005331 LABOTEST-BB LT00440975 5-HYDANTOIN ACETIC ACID HYDANTOIN-5-ACETIC ACID DL-5-(CARBOXYMETHYL)HYDANTOIN 2,4-DIOXOIMIDAZOLIDINE-5-ACETIC ACID 2,5-DIOXO-4-IMIDAZOLIDINEACETIC ACID (2,5-dioxoimidazolidin-4-yl)acetic acid 2,5-dioxo-1,3-diazolidin-4-ylacetic acid 2,5-Dioxo-1,3-diazolidin-4-ylacetic acid [(4S)-2,5-dioxoimidazolidin-4-yl]acetate [(4R)-2,5-dioxoimidazolidin-4-yl]acetate (2,5-DIOXO-IMIDAZOLIDIN-4-YL)-ACETIC ACID |
| CAS | 5427-26-9 |
| EINECS | 226-574-4 |
| InChI | InChI=1/C5H6N2O4/c8-3(9)1-2-4(10)7-5(11)6-2/h2H,1H2,(H,8,9)(H2,6,7,10,11)/p-1/t2-/m0/s1 |
2,5-DIOXO-4-IMIDAZOLIDINEACETIC ACID - Physico-chemical Properties
| Molecular Formula | C5H6N2O4 |
| Molar Mass | 158.11 |
| Density | 1.5902 (rough estimate) |
| Melting Point | 214-215°C (dec.)(lit.) |
| Boling Point | 283.16°C (rough estimate) |
| Water Solubility | 11.15g/L(temperature not stated) |
| Appearance | Crystalline Powder |
| Color | White |
| BRN | 83035 |
| pKa | 3.79±0.10(Predicted) |
| Refractive Index | 1.5090 (estimate) |
2,5-DIOXO-4-IMIDAZOLIDINEACETIC ACID - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29332100 |
| Hazard Class | IRRITANT |
2,5-DIOXO-4-IMIDAZOLIDINEACETIC ACID - Introduction
2,5-dioxo-1,3-diazolidin-4-ylacetic acid, chemical formula C6H8N2O5, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
2,5-dioxo-1,3-diazolidin-4-ylacetic acid is a colorless crystalline solid with strong acidity. It has good solubility, soluble in water and some organic solvents. 2,5-dioxo-1,3-diazolidin-4-ylacetic acid is stable in organic solvents, but it is easily hydrolyzed under alkaline conditions.
Use:
2,5-dioxo-1,3-diazolidin-4-ylacetic acid is used for some applications in organic synthesis reactions. It is useful as an acylating reagent, a nucleophile, and a stabilizing reagent. In addition, 2,5-dioxo-1,3-diazolidin-4-ylacetic acid can also be used in the synthesis of drugs, dyes and certain pesticides.
Preparation Method:
The preparation method of 2,5-dioxo-1,3-diazolidin-4-ylacetic acid is relatively simple. A common method of preparation is by reaction of hydantoin with chloroacetic acid. This reaction is usually carried out at room temperature to form the hydrochloride salt of 2,5-dioxo-1,3-diazolidin-4-ylacetic acid, which is neutralized to give pure 2,5-dioxo-1,3-diazolidin-4-ylacetic acid.
Safety Information:
2,5-dioxo-1,3-diazolidin-4-ylacetic acid has no obvious toxicity to human body under normal conditions, but long-term contact with skin and eyes should be avoided, and protective measures should be paid attention to when using. Avoid inhaling its powder or mist during operation to avoid irritation. In order to ensure safe use, 2,5-dioxo-1,3-diazolidin-4-ylacetic acid needs to be stored and handled properly, avoiding contact with strong oxidants and alkaline substances.
it should be noted that the specific use and safety of 2,5-dioxo-1,3-diazolidin-4-ylacetic acid should be evaluated and confirmed according to specific experimental conditions, and it is recommended to operate under the guidance of professionals.
Nature:
2,5-dioxo-1,3-diazolidin-4-ylacetic acid is a colorless crystalline solid with strong acidity. It has good solubility, soluble in water and some organic solvents. 2,5-dioxo-1,3-diazolidin-4-ylacetic acid is stable in organic solvents, but it is easily hydrolyzed under alkaline conditions.
Use:
2,5-dioxo-1,3-diazolidin-4-ylacetic acid is used for some applications in organic synthesis reactions. It is useful as an acylating reagent, a nucleophile, and a stabilizing reagent. In addition, 2,5-dioxo-1,3-diazolidin-4-ylacetic acid can also be used in the synthesis of drugs, dyes and certain pesticides.
Preparation Method:
The preparation method of 2,5-dioxo-1,3-diazolidin-4-ylacetic acid is relatively simple. A common method of preparation is by reaction of hydantoin with chloroacetic acid. This reaction is usually carried out at room temperature to form the hydrochloride salt of 2,5-dioxo-1,3-diazolidin-4-ylacetic acid, which is neutralized to give pure 2,5-dioxo-1,3-diazolidin-4-ylacetic acid.
Safety Information:
2,5-dioxo-1,3-diazolidin-4-ylacetic acid has no obvious toxicity to human body under normal conditions, but long-term contact with skin and eyes should be avoided, and protective measures should be paid attention to when using. Avoid inhaling its powder or mist during operation to avoid irritation. In order to ensure safe use, 2,5-dioxo-1,3-diazolidin-4-ylacetic acid needs to be stored and handled properly, avoiding contact with strong oxidants and alkaline substances.
it should be noted that the specific use and safety of 2,5-dioxo-1,3-diazolidin-4-ylacetic acid should be evaluated and confirmed according to specific experimental conditions, and it is recommended to operate under the guidance of professionals.
Last Update：2024-04-09 15:17:58
